Godoy Cruz beat Aldosivi 1-2. Aldosivi controlled the ball — 70% possession — but had nothing to show for it. The winner had to work for it: 2 from 12 shots. Best on the pitch was G. Gil Romero, rated 7.7.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 4-2-3-1·4-4-2 ARG
   Coach: F. Gago · S. MéndezReferee: A. Penel📍 Estadio José María Minella
2. 1. First half
   2. 27'
      ARG
      Yellow card
      H. Silva
   3. 42'
      ARG
      GOOOAL!E. BullaudeAssist: J. Espínola
   4. 45+1'
      ARG
      Yellow card
      R. Tesuri
   5. 45+2'
      ARG
      GOOOAL!F. Andrada
3. 1. Second half
   2. 50'
      ARG
      Yellow card
      Wilder Cartagena
   3. 54'
      ARG
      Yellow card
      F. Andrada
   4. 55'
      ARG
      GOOOAL!T. BadaloniAssist: R. Tesuri
   5. 60'
      ARG
      Substitution
      ▲F. Grahl▼E. Iniguez
   6. 67'
      ARG
      Substitution
      ▲I. Escobar▼D. Perez
   7. 73'
      ARG
      Yellow card
      L. González
   8. 74'
      ARG
      Substitution
      ▲J. Iritier▼L. Maciel
   9. 74'
      ARG
      Substitution
      ▲P. Becker▼G. A. Lodico
   10. 74'
       ARG
       Substitution
       ▲V. Burgoa▼M. Ojeda
   11. 79'
       ARG
       Substitution
       ▲M. López▼F. Milo
   12. 80'
       ARG
       Substitution
       ▲L. Rinaldi▼B. Guzmán
   13. 83'
       ARG
       Substitution
       ▲F. Henríquez▼G. Abrego
   14. 84'
       ARG
       Substitution
       ▲S. Lomonaco▼E. Bullaude
   15. 90+2'
       ARG
       Yellow card
       G. Gil Romero