Lanús beat Independiente 0-1. The winner had to work for it: 1 from 19 shots. Best on the pitch was G. Asis, rated 7.5.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 5-3-2·4-4-2 ARG
   Coach: J. Falcioni · L. ZubeldíaReferee: F. Rapallini📍 Estadio Libertadores de América
2. 1. Second half
   2. 60'
      ARG
      Substitution
      ▲J. Pacchini▼A. Soñora
   3. 64'
      ARG
      Substitution
      ▲M. Esquivel▼F. Pérez
   4. 68'
      ARG
      GOOOAL!Guillermo BurdissoAssist: N. Orsini
   5. 71'
      ARG
      Yellow card
      Guillermo Burdisso
   6. 72'
      ARG
      Substitution
      ▲B. Martinez▼A. Costa
   7. 73'
      ARG
      Substitution
      ▲S. Palacios▼Pablo Hernández
   8. 78'
      ARG
      Substitution
      ▲Lautaro Acosta▼P. De la Vega
   9. 80'
      ARG
      Yellow card
      A. Bernabei
   10. 84'
       ARG
       Substitution
       ▲G. Togni▼L. Rodriguez
   11. 85'
       ARG
       Substitution
       ▲N. Messiniti▼A. Velasco
   12. 90+2'
       ARG
       Yellow card
       G. Asis
   13. 90+3'
       ARG
       Yellow card
       M. Esquivel