Independiente beat Patronato 0-1. Best on the pitch was J. Insaurralde, rated 8.0.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 4-2-3-1·5-3-2 ARG
   Coach: I. Delfino · J. FalcioniReferee: M. Vigliano📍 Estadio Presbítero Bartolomé Grella
2. 1. First half
   2. 32'
      ARG
      Yellow card
      F. Leys
   3. 41'
      ARG
      Substitution
      ▲J. Arias▼G. Gudiño
3. 1. Second half
   2. 59'
      ARG
      Substitution
      ▲M. Palavecino▼F. Dettler
   3. 59'
      ARG
      Substitution
      ▲N. Delgadillo▼L. Comas
   4. 71'
      ARG
      GOOOAL!J. InsaurraldeAssist: S. Palacios
   5. 76'
      ARG
      Substitution
      ▲N. Franco▼J. Barinaga
   6. 76'
      ARG
      Substitution
      ▲N. Bandiera▼F. Leys
   7. 82'
      ARG
      Substitution
      ▲L. Gonzalez▼Pablo Hernández
   8. 88'
      ARG
      Substitution
      ▲T. Ortega▼J. Menendez
   9. 90+3'
      ARG
      Substitution
      ▲B. Martinez▼S. Palacios
   10. 90+3'
       ARG
       Substitution
       ▲N. Messiniti▼S. Romero