Colón beat San Lorenzo 2-0. Best on the pitch was F. Garcés, rated 7.7.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 3-4-1-2·4-3-3 ARG
   Coach: E. Domínguez · D. DaboveReferee: P. Loustau📍 Estadio Brigadier General Estanislao López
2. 1. First half
   2. 38'
      ARG
      Yellow card
      Gino Peruzzi
3. 1. Second half
   2. 62'
      ARG
      Substitution
      ▲Facundo Farías▼S. Pierotti
   3. 63'
      ARG
      Substitution
      ▲A. Castro▼N. Leguizamón
   4. 67'
      ARG
      GOOOAL!A. CastroAssist: L. Rodríguez
   5. 72'
      ARG
      Substitution
      ▲Angel Romero▼J. Ramirez
   6. 72'
      ARG
      Substitution
      ▲F. Troyansky▼F. Di Santo
   7. 79'
      ARG
      Yellow card
      F. Garcés
   8. 79'
      ARG
      Substitution
      ▲Óscar Romero▼N. Fernandez
   9. 79'
      ARG
      Substitution
      ▲A. Diaz▼L. Melano
   10. 86'
       ARG
       Substitution
       ▲F. Mura▼Eric Meza
   11. 90+1'
       ARG
       Substitution
       ▲T. Sandoval▼Luis Rodríguez
   12. 90+4'
       ARG
       Yellow card
       A. Castro
   13. 90+6'
       ARG
       GOOOAL!T. Sandoval