Talleres and Newell's Old Boys drew 2-2. Newell's Old Boys played with ten from minute 76. Best on the pitch was J. Soñora, rated 7.6.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 4-2-3-1·4-2-3-1 ARG
   Coach: A. Medina · F. KudelkaReferee: F. Tello📍 Estadio Mario Alberto Kempes
2. 1. First half
   2. 25'
      ARG
      Yellow card
      A. Rodríguez
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲Pablo Pérez▼Juan Sforza
   3. 50'
      ARG
      GOOOAL!Mateo ReteguiAssist: N. Tenaglia
   4. 52'
      ARG
      Yellow card
      Guilherme Parede
   5. 57'
      ARG
      Substitution
      ▲Justo Giani▼A. Rodríguez
   6. 57'
      ARG
      GOOOAL!I. ScoccoPenalty
   7. 64'
      ARG
      Substitution
      ▲D. Valoyes▼Guilherme Parede
   8. 65'
      ARG
      GOOOAL!Julián FernándezAssist: M. Rodríguez
   9. 68'
      ARG
      Yellow card
      C. Lema
   10. 70'
       ARG
       Substitution
       ▲Michael Santos▼J. Mendez
   11. 73'
       ARG
       Yellow card
       R. Pérez
   12. 74'
       ARG
       Substitution
       ▲B. Rivero▼I. Scocco
   13. 76'
       ARG
       Red card
       Justo Giani
   14. 80'
       ARG
       Substitution
       ▲A. Martino▼Augusto Schott
   15. 80'
       ARG
       Substitution
       ▲F. Mac Allister▼F. Navarro
   16. 84'
       ARG
       GOOOAL!D. ValoyesAssist: J. Soñora
   17. 85'
       ARG
       Substitution
       ▲M. Fórmica▼Maximiliano Rodríguez
   18. 85'
       ARG
       Substitution
       ▲J. Cacciabue▼J. Marcioni