Independiente beat Gimnasia de La Plata 1-0. The winner had to work for it: 1 from 12 shots. Best on the pitch was D. Blanco, rated 8.0.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 5-3-2·4-4-2 ARG
   Coach: J. Falcioni · M. MesseraReferee: P. Dóvalo📍 Estadio Libertadores de América
2. 1. First half
   2. -5'
      ARG
      Yellow card
      J. Menendez
   3. 4'
      ARG
      Yellow card
      D. Blanco
   4. 19'
      ARG
      Substitution
      ▲L. Morales▼M. Coronel
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲L. Gonzalez▼Pablo Hernández
   3. 59'
      ARG
      Yellow card
      J. Insaurralde
   4. 62'
      ARG
      Substitution
      ▲A. Velasco▼S. Barreto
   5. 66'
      ARG
      GOOOAL!S. Romero
   6. 68'
      ARG
      Substitution
      ▲A. Arregui▼S. Palacios
   7. 68'
      ARG
      Substitution
      ▲M. Comba▼M. Miranda
   8. 68'
      ARG
      Substitution
      ▲Lucas Barrios▼L. Contín
   9. 85'
      ARG
      Substitution
      ▲T. Ortega▼G. Togni
   10. 86'
       ARG
       Substitution
       ▲A. Costa▼J. Menendez
   11. 89'
       ARG
       Yellow card
       M. Weigandt