Argentinos Juniors beat Godoy Cruz 2-0. The winner had to work for it: 2 from 17 shots. Best on the pitch was J. Cabrera, rated 7.6.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 3-4-2-1·4-2-3-1 ARG
   Coach: G. Milito · S. MéndezReferee: P. Loustau📍 Estadio Diego Armando Maradona
2. 1. First half
   2. 2'
      ARG
      Yellow card
      Damián Pérez
   3. 18'
      ARG
      GOOOAL!Gabriel ÁvalosAssist: F. Moyano
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲V. Burgoa▼M. Ojeda
   3. 47'
      ARG
      Substitution
      ▲G. Florentin▼Gabriel Hauche
   4. 56'
      ARG
      Substitution
      ▲T. Badaloni▼C. Colmán
   5. 56'
      ARG
      Substitution
      ▲A. Aguirre▼L. González
   6. 59'
      ARG
      Substitution
      ▲P. Minissale▼C. Quintana
   7. 61'
      ARG
      Yellow card
      P. Minissale
   8. 63'
      ARG
      Substitution
      ▲M. Ramirez▼G. Abrego
   9. 66'
      ARG
      GOOOAL!Elías GómezAssist: Javier Cabrera
   10. 70'
       ARG
       Substitution
       ▲M. Pisano▼J. Cabrera
   11. 70'
       ARG
       Substitution
       ▲Fausto Vera▼M. Romero
   12. 70'
       ARG
       Substitution
       ▲E. Herrera▼Gabriel Ávalos
   13. 75'
       ARG
       Yellow card
       R. Tesuri
   14. 76'
       ARG
       Yellow card
       G. Ferrari
   15. 77'
       ARG
       Substitution
       ▲S. Lomonaco▼E. Bullaude
   16. 80'
       ARG
       Yellow card
       F. Moyano
   17. 90+4'
       ARG
       Yellow card
       M. Dos Santos