Defensa y Justicia and Talleres drew 2-2. Defensa y Justicia played with ten from minute 90. Best on the pitch was Miguel Merentiel, rated 7.6.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 4-1-4-1·4-2-3-1 ARG
   Coach: S. Beccacece · A. MedinaReferee: F. Rapallini📍 Estadio Norberto Tito Tomaghello
2. 1. First half
   2. 2'
      ARG
      GOOOAL!Miguel MerentielAssist: C. Rius
   3. 9'
      ARG
      Yellow card
      J. Rodriguez
   4. 39'
      ARG
      Yellow card
      R. Herrera
   5. 43'
      ARG
      Own goalN. Breitenbruch
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲C. Rotondi▼J. González
   3. 46'
      ARG
      Substitution
      ▲Enzo Fernández▼V. Larralde
   4. 46'
      ARG
      Substitution
      ▲R. Loaiza▼R. Herrera
   5. 54'
      ARG
      GOOOAL!L. T. Escalante
   6. 57'
      ARG
      Yellow card
      P. Hincapie
   7. 61'
      ARG
      Substitution
      ▲B. Romero▼Miguel Merentiel
   8. 63'
      ARG
      Substitution
      ▲Michael Santos▼F. Fragapane
   9. 66'
      ARG
      Own goalJ. Rodriguez
   10. 78'
       ARG
       Substitution
       ▲T. Ortiz▼C. Rius
   11. 79'
       ARG
       Substitution
       ▲Mateo Retegui▼Guilherme Parede
   12. 80'
       ARG
       Yellow card
       R. Pérez
   13. 90+3'
       ARG
       Red card
       N. Breitenbruch