Argentinos Juniors and Central Córdoba (Santiago del Estero) drew 0-0.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   Coach: G. Milito · G. ColeoniReferee: P. Dóvalo📍 Estadio Diego Armando Maradona
2. 1. First half
   2. 8'
      ARG
      Yellow card
      C. Vega
   3. 38'
      ARG
      Yellow card
      K. Mac Allister
   4. 41'
      ARG
      Yellow card
      D. Rentería
3. 1. Second half
   2. 61'
      ARG
      Substitution
      ▲Gabriel Hauche▼J. Gomez
   3. 62'
      ARG
      Substitution
      ▲S. Rosales▼L. Brochero
   4. 62'
      ARG
      Substitution
      ▲H. Lopez▼G. Bettini
   5. 70'
      ARG
      Substitution
      ▲J. González▼L. Sequeira
   6. 74'
      ARG
      Yellow card
      F. Cerro
   7. 74'
      ARG
      Substitution
      ▲M. Pisano▼G. Carabajal
   8. 74'
      ARG
      Substitution
      ▲D. Sosa▼J. Cabrera
   9. 78'
      ARG
      Substitution
      ▲P. Argañaraz▼M. Gimenez
   10. 78'
       ARG
       Substitution
       ▲J. Galeano▼F. Cerro
   11. 83'
       ARG
       Substitution
       ▲E. Herrera▼Gabriel Ávalos
   12. 83'
       ARG
       Substitution
       ▲I. Colman▼G. Florentin
   13. 85'
       ARG
       Yellow card
       Miguel Torren