Atlético Tucumán beat Vélez Sarsfield 2-0. Vélez Sarsfield controlled the ball — 64% possession — but had nothing to show for it. The winner had to work for it: 2 from 17 shots. Best on the pitch was C. Lucchetti, rated 8.2.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 4-4-2·3-4-2-1 ARG
   Coach: O. De Felippe · M. PellegrinoReferee: S. Trucco📍 Estadio Monumental Presidente José Fierro
2. 1. First half
   2. 13'
      ARG
      GOOOAL!Oscar BenítezAssist: J. Toledo
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲J. Lucero▼F. Ortega
   3. 49'
      ARG
      Yellow card
      L. Heredia
   4. 49'
      ARG
      Yellow card
      H. De La Fuente
   5. 56'
      ARG
      Substitution
      ▲A. Lagos▼Oscar Benítez
   6. 63'
      ARG
      Yellow card
      G. Risso
   7. 66'
      ARG
      Substitution
      ▲Thiago Almada▼L. Janson
   8. 66'
      ARG
      Substitution
      ▲L. Orellano▼H. De La Fuente
   9. 68'
      ARG
      Substitution
      ▲A. Lotti▼L. Heredia
   10. 68'
       ARG
       Substitution
       ▲F. Mussis▼A. Bustos
   11. 76'
       ARG
       GOOOAL!A. Lotti
   12. 82'
       ARG
       Substitution
       ▲F. Mancuello▼A. Mulet
   13. 83'
       ARG
       Substitution
       ▲R. Centurión▼A. Bouzat
   14. 87'
       ARG
       Yellow card
       M. Ortiz
   15. 89'
       ARG
       Substitution
       ▲M. Alustiza▼J. Toledo
   16. 90'
       ARG
       Yellow card
       F. Mancuello
   17. 90+3'
       ARG
       Yellow card
       C. Erbes