Estudiantes de La Plata and Gimnasia de La Plata drew 0-0. Gimnasia de La Plata played with ten from minute 75. Best on the pitch was M. Melluso, rated 7.9.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2021
   ARG 4-4-2·4-2-3-1 ARG
   Coach: R. Zielinski · M. MesseraReferee: D. Herrera📍 Estadio Jorge Luis Hirschi
2. 1. First half
   2. 27'
      ARG
      Yellow card
      B. Alemán
3. 1. Second half
   2. 57'
      ARG
      Yellow card
      F. Noguera
   3. 59'
      ARG
      Substitution
      ▲L. Rodríguez▼Nicolas Pasquini
   4. 60'
      ARG
      Substitution
      ▲Esteban Fernando González▼Á. Gonzalez
   5. 62'
      ARG
      Substitution
      ▲Pérez García▼M. Miranda
   6. 64'
      ARG
      Yellow card
      L. Morales
   7. 67'
      ARG
      Yellow card
      Harrinson Mancilla
   8. 72'
      ARG
      Yellow card
      M. Melluso
   9. 74'
      ARG
      Substitution
      ▲M. Castro▼M. Cauteruccio
   10. 74'
       ARG
       Substitution
       ▲D. Ayala▼I. Gomez
   11. 75'
       ARG
       Yellow card
       Harrinson Mancilla
   12. 75'
       ARG
       Red card
       Harrinson Mancilla
   13. 77'
       ARG
       Substitution
       ▲E. Cecchini▼E. Ramirez
   14. 78'
       ARG
       Yellow card
       A. Rogel
   15. 86'
       ARG
       Yellow card
       M. Castro
   16. 89'
       ARG
       Substitution
       ▲J. Apaolaza▼J. Rodriguez
   17. 89'
       ARG
       Substitution
       ▲L. Contín▼J. Carbonero