Colón beat Central Córdoba (Santiago del Estero) 1-0. The winner had to work for it: 1 from 12 shots. Best on the pitch was P. Goltz, rated 7.9.

1. 0'
   ⚽Kick-off
   Torneo 2021
   ARG 4-1-4-1·4-3-1-2 ARG
   Coach: E. Domínguez · S. RondinaReferee: D. Herrera📍 Estadio Brigadier General Estanislao López
2. 1. First half
   2. 19'
      ARG
      Yellow card
      Christian Bernardi
   3. 26'
      ARG
      Yellow card
      O. Salomon
   4. 33'
      ARG
      GOOOAL!R. AliendroAssist: F. Mura
   5. 40'
      ARG
      Yellow card
      C. Lattanzio
   6. 45+4'
      ARG
      Yellow card
      Facundo Farías
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲A. Martinez▼L. Brochero
   3. 63'
      ARG
      Yellow card
      F. Lértora
   4. 68'
      ARG
      Substitution
      ▲Y. Góez▼Juan C. Ferreyra
   5. 78'
      ARG
      Substitution
      ▲C. Riaño▼L. Sequeira
   6. 78'
      ARG
      Substitution
      ▲L. Melano▼C. Lattanzio
   7. 85'
      ARG
      Substitution
      ▲F. Garcés▼Christian Bernardi
   8. 86'
      ARG
      Substitution
      ▲J. Galeano▼J. Soraire
   9. 87'
      ARG
      Substitution
      ▲P. Argañaraz▼C. Vega
   10. 90+4'
       ARG
       Yellow card
       A. Castro