Independiente beat Arsenal de Sarandí 1-0. The winner had to work for it: 1 from 15 shots. Best on the pitch was L. Romero, rated 7.9.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-2-3-1·4-1-4-1 ARG
   Coach: E. Domínguez · L. MadelónReferee: L. Rey Hilfer📍 Estadio Libertadores de América
2. 1. First half
   2. 34'
      ARG
      Yellow card
      A. Vigo
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲M. Pitton▼L. Picco
   3. 52'
      ARG
      Yellow card
      L. Suarez
   4. 58'
      ARG
      Substitution
      ▲G. Togni▼T. Ortega
   5. 58'
      ARG
      Substitution
      ▲T. A. Pozzo▼A. Soñora
   6. 61'
      ARG
      Substitution
      ▲A. Diaz▼S. Lomonaco
   7. 61'
      ARG
      Substitution
      ▲B. Sanchez▼A. Antilef
   8. 65'
      ARG
      Yellow card
      Juan M. Insaurralde
   9. 68'
      ARG
      Substitution
      ▲Damián Pérez▼L. Suarez
   10. 71'
       ARG
       Substitution
       ▲R. L. Marquez De Meneses▼C. Benavídez
   11. 72'
       ARG
       Substitution
       ▲E. Torres▼L. Brochero
   12. 75'
       ARG
       GOOOAL!T. A. PozzoAssist: S. Barreto
   13. 81'
       ARG
       Substitution
       ▲L. Rodriguez▼Leandro Fernandez
   14. 82'
       ARG
       Yellow card
       L. Romero
   15. 87'
       ARG
       Yellow card
       G. Goni