Gimnasia de La Plata beat San Lorenzo 1-0. The winner had to work for it: 1 from 20 shots. San Lorenzo played with ten from minute 41. Best on the pitch was S. Torrico, rated 9.3.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-2-3-1·4-4-2 ARG
   Coach: N. Gorosito · P. TroglioReferee: F. Echenique📍 Estadio Juan Carmelo Zerillo
2. 1. First half
   2. 21'
      ARG
      Yellow card
      Y. Gordillo
   3. 41'
      ARG
      Yellow card
      Y. Gordillo
   4. 41'
      ARG
      Red card
      Y. Gordillo
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲Malcom Braida▼N. Fernandez
   3. 51'
      ARG
      Yellow card
      B. Alemán
   4. 55'
      ARG
      Yellow card
      E. Cecchini
   5. 57'
      ARG
      GOOOAL!Cristian Tarragona
   6. 63'
      ARG
      Substitution
      ▲A. Martegani▼Gino Peruzzi
   7. 63'
      ARG
      Substitution
      ▲E. García▼Adam Bareiro
   8. 72'
      ARG
      Yellow card
      G. Luján
   9. 75'
      ARG
      Substitution
      ▲L. Chavez▼Ramón Sosa
   10. 75'
       ARG
       Substitution
       ▲A. Sabella▼Néstor Ortigoza
   11. 79'
       ARG
       Yellow card
       A. Martegani
   12. 81'
       ARG
       Substitution
       ▲A. Cardozo▼E. Cecchini
   13. 82'
       ARG
       Substitution
       ▲F. Soldano▼Cristian Tarragona
   14. 86'
       ARG
       Substitution
       ▲N. Barrios▼R. Centurión
   15. 88'
       ARG
       Yellow card
       E. García
   16. 90+3'
       ARG
       Substitution
       ▲B. Dominguez▼B. Alemán
   17. 90+3'
       ARG
       Substitution
       ▲T. Muro▼J. Carbonero