Aldosivi and Central Córdoba (Santiago del Estero) drew 0-0. Best on the pitch was I. Ramirez, rated 8.2.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-2-3-1·4-2-3-1 ARG
   Coach: M. Palermo · S. RondinaReferee: N. Pitana📍 Estadio José María Minella
2. 1. First half
   2. 34'
      ARG
      Yellow card
      F. Roman
   3. 40'
      ARG
      Yellow card
      Valentín Mancini
3. 1. Second half
   2. 59'
      ARG
      Substitution
      ▲Santiago Martín Silva▼T. Martínez
   3. 59'
      ARG
      Substitution
      ▲Matías Morello▼C. Meli
   4. 63'
      ARG
      Substitution
      ▲P. Argañaraz▼J. Kaprof
   5. 64'
      ARG
      Yellow card
      E. Iniguez
   6. 67'
      ARG
      Substitution
      ▲J. Zacaría▼Valentín Mancini
   7. 73'
      ARG
      Substitution
      ▲G. Rios▼F. Grahl
   8. 74'
      ARG
      Substitution
      ▲S. Ribas▼R. López
   9. 77'
      ARG
      Substitution
      ▲R. Lucero▼M. Pisano
   10. 77'
       ARG
       Substitution
       ▲Andrés L. Ríos▼E. Iniguez
   11. 85'
       ARG
       Substitution
       ▲R. Montes▼F. Gonzalez