Newell's Old Boys beat Talleres 1-2. Talleres controlled the ball — 62% possession — but had nothing to show for it. Best on the pitch was C. Lema, rated 8.0.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-2-3-1·4-2-3-1 ARG
   Coach: G. Hoyos · J. SanguinettiReferee: D. Herrera📍 Estadio Mario Alberto Kempes
2. 1. First half
   2. 20'
      ARG
      Yellow card
      Julián Fernández
   3. 22'
      ARG
      Yellow card
      Federico Girotti
   4. 24'
      ARG
      Yellow card
      E. Batalla
3. 1. Second half
   2. 54'
      ARG
      Substitution
      ▲R. Garro▼H. Fertoli
   3. 55'
      ARG
      Yellow card
      R. Pérez
   4. 55'
      ARG
      Yellow card
      Pablo Pérez
   5. 57'
      ARG
      GOOOAL!N. CastroAssist: J. García
   6. 60'
      ARG
      Yellow card
      G. Herrera
   7. 62'
      ARG
      GOOOAL!C. LemaPenalty
   8. 63'
      ARG
      Yellow card
      E. Díaz
   9. 66'
      ARG
      Substitution
      ▲M. Portillo▼Pablo Pérez
   10. 66'
       ARG
       Substitution
       ▲G. Velazquez▼W. Ditta
   11. 69'
       ARG
       Substitution
       ▲I. Lago▼M. Godoy
   12. 71'
       ARG
       Substitution
       ▲D. Reasco▼J. Garcia
   13. 71'
       ARG
       Substitution
       ▲R. Sordo▼J. Garro
   14. 71'
       ARG
       Substitution
       ▲G. Balzi▼N. Castro
   15. 81'
       ARG
       Yellow card
       A. Mendez
   16. 90+3'
       ARG
       GOOOAL!Federico GirottiAssist: E. Díaz