Colón and Unión drew 0-0. Best on the pitch was R. Delgado, rated 7.9.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 3-5-2·4-4-2 ARG
   Coach: J. Falcioni · G. MunúaReferee: N. Pitana📍 Estadio Brigadier General Estanislao López
2. 1. First half
   2. 16'
      ARG
      Substitution
      ▲L. Esquivel▼C. Corvalan
   3. 39'
      ARG
      Yellow card
      Diego Polenta
3. 1. Second half
   2. 54'
      ARG
      Yellow card
      L. Ramos
   3. 64'
      ARG
      Substitution
      ▲D. Juárez▼I. Machuca
   4. 65'
      ARG
      Substitution
      ▲M. Peralta▼L. Ramos
   5. 71'
      ARG
      Yellow card
      J. Nardoni
   6. 77'
      ARG
      Yellow card
      R. Aliendro
   7. 77'
      ARG
      Substitution
      ▲Facundo Farías▼Christian Bernardi
   8. 79'
      ARG
      Substitution
      ▲M. Gallegos▼M. Luna Diale
   9. 81'
      ARG
      Substitution
      ▲R. Abila▼L. Beltrán
   10. 81'
       ARG
       Substitution
       ▲C. Vega▼R. Aliendro
   11. 86'
       ARG
       Yellow card
       L. Esquivel