Patronato beat San Lorenzo 1-2. San Lorenzo controlled the ball — 62% possession — but had nothing to show for it. The winner had to work for it: 2 from 15 shots. San Lorenzo played with ten from minute 64. Best on the pitch was E. Cerutti, rated 7.7.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-3-1-2·4-4-2 ARG
   Coach: F. Berón · F. SavaReferee: J. Baliño📍 Estadio Pedro Bidegaín
2. 1. First half
   2. 17'
      ARG
      GOOOAL!A. RodríguezAssist: J. Herrera
   3. 25'
      ARG
      Yellow card
      F. Leys
   4. 31'
      ARG
      Yellow card
      L. Kruspzky
   5. 42'
      ARG
      Yellow card
      N. Castro
3. 1. Second half
   2. 46'
      ARG
      Substitution
      ▲R. Centurión▼Ezequiel Herrera
   3. 54'
      ARG
      Substitution
      ▲T. Banega▼S. Medina
   4. 54'
      ARG
      Substitution
      ▲S. Ojeda▼A. Rodríguez
   5. 63'
      ARG
      VAR review
      Nicolás Ezequiel Fernández Mercau
   6. 64'
      ARG
      Red card
      Nicolás Ezequiel Fernández Mercau
   7. 67'
      ARG
      GOOOAL!G. GudiñoAssist: R. Lozano
   8. 69'
      ARG
      VAR review
      G. Gudiño
   9. 70'
      ARG
      Substitution
      ▲Malcom Braida▼Cristián Zapata
   10. 71'
       ARG
       Own goalS. Ojeda
   11. 76'
       ARG
       Substitution
       ▲D. García▼G. Gudiño
   12. 78'
       ARG
       Substitution
       ▲N. Blandi▼Adam Bareiro
   13. 80'
       ARG
       Substitution
       ▲Lucas Barrios▼J. Herrera
   14. 81'
       ARG
       Yellow card
       L. Geminiani
   15. 81'
       ARG
       Substitution
       ▲L. Geminiani▼O. Paz Benítez
   16. 90'
       ARG
       Substitution
       ▲N. Fernandez▼A. Martegani