Rosario Central beat Independiente 3-0. Independiente controlled the ball — 68% possession — but had nothing to show for it. Independiente played with ten from minute 89. Best on the pitch was M. Benítez, rated 8.3.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-1-3-2·4-4-2 ARG
   Coach: L. Somoza · E. DomínguezReferee: N. Lamolina📍 Estadio Gigante de Arroyito
2. 1. First half
   2. 2'
      ARG
      GOOOAL!M. RubenAssist: M. Benítez
   3. 17'
      ARG
      Yellow card
      S. Barreto
3. 1. Second half
   2. 53'
      ARG
      Substitution
      ▲M. Tanlongo▼L. Gamba
   3. 61'
      ARG
      Substitution
      ▲J. Cazares▼C. Benavídez
   4. 61'
      ARG
      Substitution
      ▲D. Blanco▼Damián Batallini
   5. 61'
      ARG
      Substitution
      ▲Leandro Fernandez▼T. A. Pozzo
   6. 61'
      ARG
      Substitution
      ▲J. Romero▼L. Benegas
   7. 67'
      ARG
      Substitution
      ▲W. Montoya▼A. Veliz
   8. 67'
      ARG
      Substitution
      ▲Julián Velázquez▼D. Martinez
   9. 70'
      ARG
      Substitution
      ▲Milton Caraglio▼M. Ruben
   10. 71'
       ARG
       GOOOAL!Julián VelázquezAssist: C. Yacob
   11. 73'
       ARG
       GOOOAL!W. MontoyaAssist: M. Benítez
   12. 82'
       ARG
       Yellow card
       L. Ferreyra
   13. 82'
       ARG
       Yellow card
       L. Romero
   14. 88'
       ARG
       Yellow card
       J. Insaurralde
   15. 89'
       ARG
       Yellow card
       J. Insaurralde
   16. 89'
       ARG
       Red card
       J. Insaurralde
   17. 89'
       ARG
       Substitution
       ▲R. L. Marquez De Meneses▼A. Soñora
   18. 90+4'
       ARG
       Yellow card
       T. Ortega