San Lorenzo beat Newell's Old Boys 1-2. Newell's Old Boys controlled the ball — 72% possession — but had nothing to show for it. The winner had to work for it: 2 from 15 shots. Best on the pitch was F. Gattoni, rated 7.6.

1. 0'
   ⚽Kick-off
   Copa de la Liga Profesional 2022
   ARG 4-2-3-1·3-5-2 ARG
   Coach: J. Sanguinetti · F. BerónReferee: D. Herrera📍 Estadio Marcelo Alberto Bielsa
2. 1. First half
   2. 22'
      ARG
      GOOOAL!A. MarteganiAssist: Nicolás Emanuel Fernández
   3. 26'
      ARG
      Yellow card
      F. Gonzalez
   4. 43'
      ARG
      Yellow card
      Justo Giani
3. 1. Second half
   2. 52'
      ARG
      Yellow card
      Pablo Pérez
   3. 54'
      ARG
      Substitution
      ▲J. Garro▼Pablo Pérez
   4. 54'
      ARG
      Substitution
      ▲N. Castro▼N. Funez
   5. 60'
      ARG
      GOOOAL!F. Gattoni
   6. 63'
      ARG
      Substitution
      ▲G. Rossi▼D. Reasco
   7. 67'
      ARG
      Yellow card
      Y. Gordillo
   8. 67'
      ARG
      Substitution
      ▲Ezequiel Herrera▼Agustín Giay
   9. 68'
      ARG
      GOOOAL!C. LemaAssist: F. González
   10. 72'
       ARG
       VAR review
       Justo Giani
   11. 79'
       ARG
       Substitution
       ▲G. Balzi▼F. Gonzalez
   12. 79'
       ARG
       Substitution
       ▲I. Leguizamon▼N. Fernandez
   13. 79'
       ARG
       Substitution
       ▲F. Perruzzi▼A. Martegani
   14. 89'
       ARG
       Substitution
       ▲S. Rosane▼Y. Gordillo
   15. 89'
       ARG
       Substitution
       ▲N. Blandi▼E. Cerutti
   16. 90+6'
       ARG
       Yellow card
       G. Rossi