Independiente beat Newell's Old Boys 1-0. The winner had to work for it: 1 from 19 shots. Best on the pitch was L. Morales, rated 7.6.

1. 0'
   ⚽Kick-off
   Liga Profesional 2022
   ARG 4-2-3-1·4-2-3-1 ARG
   Coach: J. Serrizuela · G. TognarelliReferee: F. Rapallini📍 Estadio Libertadores de América
2. 1. First half
   2. 14'
      ARG
      Yellow card
      J. Garro
   3. 20'
      ARG
      Yellow card
      Iván Marcone
   4. 27'
      ARG
      Yellow card
      W. Ditta
3. 1. Second half
   2. 52'
      ARG
      Substitution
      ▲M. Campagnaro▼M. Luciano
   3. 62'
      ARG
      GOOOAL!L. Benegas
   4. 67'
      ARG
      Yellow card
      Damián Batallini
   5. 69'
      ARG
      Substitution
      ▲S. Ayala▼L. Benegas
   6. 70'
      ARG
      Substitution
      ▲G. Balzi▼Julián Fernández
   7. 70'
      ARG
      Substitution
      ▲A. Mendez▼G. Velazquez
   8. 71'
      ARG
      Substitution
      ▲F. Gonzalez▼J. Garro
   9. 76'
      ARG
      Substitution
      ▲J. Vallejo▼R. L. Marquez De Meneses
   10. 76'
       ARG
       Substitution
       ▲L. Gonzalez▼T. A. Pozzo
   11. 82'
       ARG
       Substitution
       ▲A. Soñora▼L. Romero
   12. 89'
       ARG
       Yellow card
       Juan Sforza