Colo Colo beat Bucaramanga 1-0. The winner had to work for it: 1 from 13 shots. Bucaramanga played with ten from minute 33. Best on the pitch was J. Correa, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2025
   CHI —·4-2-3-1 COL
   Coach: — · Leonel de Jesús Álvarez ZuletaReferee: Kevin Ortega, Peru📍 Estadio Monumental David Arellano
2. 1. First half
   2. 20'
      CHI
      Yellow card
      T. Alarcón
   3. 23'
      COL
      Yellow card
      A. Gutiérrez
   4. 26'
      CHI
      GOOOAL!J. Correa
   5. 33'
      COL
      Yellow card
      A. Gutiérrez
   6. 33'
      COL
      Red card
      A. Gutiérrez
   7. 38'
      COL
      Substitution
      ▲M. S. Jimenez▼F. Castaneda
3. 1. Second half
   2. 46'
      CHI
      Substitution
      ▲E. Pavez▼T. Alarcón
   3. 60'
      CHI
      Yellow card
      E. Pavez
   4. 62'
      COL
      Yellow card
      Fabián Sambueza
   5. 67'
      COL
      Substitution
      ▲D. Chavez▼L. Flores
   6. 67'
      COL
      Substitution
      ▲J. Vásquez▼Fabián Sambueza
   7. 71'
      CHI
      Yellow card
      Óscar Opazo
   8. 77'
      CHI
      Substitution
      ▲D. Gutiérrez▼Óscar Opazo
   9. 78'
      CHI
      Substitution
      ▲C. Zavala▼Víctor Felipe Méndez
   10. 81'
       CHI
       VAR review
       Lucas Cepeda
   11. 83'
       COL
       Yellow card
       L. Pons
   12. 85'
       CHI
       Yellow card
       Vicente Pizarro
   13. 85'
       COL
       Yellow card
       J. Vásquez
   14. 86'
       COL
       Yellow card
       Fabry
   15. 87'
       COL
       Substitution
       ▲J. Mosquera▼K. Londono
   16. 90+5'
       COL
       Yellow card
       D. Chavez