Sao Paulo knocked Atletico Nacional out on penalties 4-3, after a 1-1 draw. Atletico Nacional played with ten from minute 70. Best on the pitch was A. Morelos, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2025
   BRA 3-5-2·4-2-3-1 COL
   Coach: Hernán Jorge Crespo · Diego Alejandro Arias HincapiéReferee: Maximiliano Ramírez📍 Estadio Do MorumBIS
2. 1. First half
   2. 3'
      BRA
      GOOOAL!André SilvaAssist: A. Franco
   3. 18'
      COL
      Yellow card
      Edwin Cardona
   4. 18'
      BRA
      Yellow card
      Cédric Soares
3. 1. Second half
   2. 50'
      COL
      Yellow card
      J. Zapata
   3. 56'
      BRA
      Substitution
      ▲M. Uribe▼J. Zapata
   4. 60'
      COL
      Substitution
      ▲Lucas Moura▼Rodriguinho
   5. 70'
      BRA
      Yellow card
      N. Ferraresi
   6. 70'
      COL
      Yellow card
      Edwin Cardona
   7. 70'
      COL
      Red card
      Edwin Cardona
   8. 70'
      COL
      GOOOAL!A. MorelosPenalty
   9. 74'
      COL
      Substitution
      ▲Ferreira▼André Silva
   10. 78'
       BRA
       Yellow card
       Agustín Franco
   11. 86'
       BRA
       Substitution
       ▲J. Bauza▼Marlos Moreno
   12. 88'
       COL
       Substitution
       ▲Henrique Carmo▼Agustín Franco
   13. 90+7'
       COL
       Yellow card
       J. Campuzano
   14. 90+8'
       COL
       Yellow card
       A. Roman