Club Nacional beat Zamora FC 1-0. The winner had to work for it: 1 from 17 shots. Best on the pitch was Chori Castro, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2019
   URU 4-2-3-1·4-2-3-1 VEN
   Coach: Á. Gutiérrez · A. CañasReferee: Fernando Espinoza, Argentina📍 Gran Parque Central
2. 1. First half
   2. 42'
      URU
      Yellow card
      G. Corujo
   3. 45'
      URU
      Yellow card
      R. Amaral
   4. 45'
      URU
      Yellow card
      G. Cotugno
   5. 45'
      VEN
      Yellow card
      Ignacio Gonzalez
3. 1. Second half
   2. 51'
      URU
      GOOOAL!Gonzalo BergessioAssist: Matías Viña
   3. 55'
      VEN
      Yellow card
      Mayker González
   4. 60'
      VEN
      Substitution
      ▲Gustavo Rojas▼Maikol Quintero
   5. 65'
      URU
      Yellow card
      Gabriel Neves
   6. 67'
      URU
      Substitution
      ▲B. Ocampo▼Chori Castro
   7. 68'
      URU
      Substitution
      ▲J. Arzura▼R. Amaral
   8. 73'
      VEN
      Yellow card
      Guillermo Paiva
   9. 81'
      VEN
      Substitution
      ▲Angel Osorio▼Pedro Ramirez
   10. 82'
       URU
       Yellow card
       Gonzalo Bergessio
   11. 84'
       VEN
       Yellow card
       Jose Soto
   12. 84'
       URU
       Substitution
       ▲Octavio Rivero▼Gonzalo Bergessio
   13. 90'
       VEN
       Substitution
       ▲Edixon Jose Mena Ortiz▼Jáder Maza