Santos beat Defensa y Justicia 1-2. Defensa y Justicia controlled the ball — 60% possession — but had nothing to show for it. Best on the pitch was Yeferson Soteldo, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2020
   ARG 3-5-2·3-4-3 BRA
   Coach: H. Crespo · Jesualdo FerreiraReferee: G. Tejera📍 Estadio Norberto Tito Tomaghello
2. 1. First half
   2. 22'
      BRA
      Yellow card
      Lucas Verissimo
   3. 37'
      BRA
      Yellow card
      Luan Peres
   4. 45+1'
      ARG
      GOOOAL!J. RodriguezAssist: N. Cardozo
3. 1. Second half
   2. 51'
      BRA
      Yellow card
      Evandro
   3. 55'
      BRA
      Yellow card
      Carlos Sánchez
   4. 58'
      BRA
      Substitution
      ▲Jobson▼Evandro
   5. 69'
      ARG
      Substitution
      ▲B. Ojeda▼N. Cardozo
   6. 69'
      BRA
      Substitution
      ▲Kaio Jorge▼Yuri Alberto
   7. 72'
      BRA
      GOOOAL!JobsonAssist: Y. Soteldo
   8. 78'
      ARG
      Yellow card
      R. Botta
   9. 79'
      ARG
      Substitution
      ▲F. Márquez▼Guido Mainero
   10. 79'
       ARG
       Substitution
       ▲E. Coacci▼R. Botta
   11. 85'
       BRA
       Substitution
       ▲Felipe Jonatan▼Luiz Felipe
   12. 86'
       BRA
       GOOOAL!Kaio Jorge
   13. 87'
       BRA
       Yellow card
       Kaio Jorge
   14. 90'
       ARG
       Yellow card
       M. Benítez