Union Espanola beat Independiente del Valle 1-0. Independiente del Valle controlled the ball — 64% possession — but had nothing to show for it. Best on the pitch was T. Galdames, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   CHI 4-2-3-1·3-5-2 ECU
   Coach: J. Pellicer · Renato PaivaReferee: Wilton Pereira Sampaio📍 Estadio Santa Laura-Universidad SEK
2. 1. First half
   2. 40'
      ECU
      Yellow card
      L. Segovia
3. 1. Second half
   2. 52'
      CHI
      Yellow card
      Carlos Palacios
   3. 56'
      ECU
      Own goalB. Caicedo
   4. 58'
      CHI
      Yellow card
      I. Lemmo
   5. 61'
      CHI
      Substitution
      ▲Alejandro Chumacero▼I. Lemmo
   6. 65'
      CHI
      Yellow card
      G. Villagra
   7. 69'
      CHI
      Substitution
      ▲C. Palacios▼Patricio Rubio
   8. 69'
      ECU
      Substitution
      ▲P. Vite▼C. Pellerano
   9. 69'
      ECU
      Substitution
      ▲Jhoanner Chavez▼B. Caicedo
   10. 71'
       ECU
       Yellow card
       Jhoanner Chavez
   11. 81'
       ECU
       Substitution
       ▲B. Montenegro▼J. Escobar
   12. 81'
       ECU
       Substitution
       ▲J. Sánchez▼A. Landázuri
   13. 87'
       ECU
       Substitution
       ▲E. Mera▼C. Ortiz
   14. 88'
       CHI
       Substitution
       ▲L. Pavez▼R. Farfán