Bolívar beat Junior 2-1. The winner had to work for it: 2 from 31 shots. Best on the pitch was Alex Granell, rated 7.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   BOL 4-2-3-1·4-1-4-1 COL
   Coach: Natxo González · L. PereaReferee: Wilton Pereira Sampaio📍 Estadio Hernando Siles
2. 1. First half
   2. 4'
      BOL
      GOOOAL!L. Ramos
   3. 10'
      COL
      GOOOAL!G. MeraAssist: J. Pajoy
   4. 12'
      BOL
      Yellow card
      L. Justiniano
   5. 19'
      COL
      Yellow card
      Homer Martinez
3. 1. Second half
   2. 46'
      COL
      Substitution
      ▲Fabián Sambueza▼Larry Vásquez
   3. 48'
      BOL
      GOOOAL!D. BejaranoAssist: L. Ramos
   4. 62'
      COL
      Yellow card
      W. Ditta
   5. 70'
      BOL
      Substitution
      ▲Bruno Miranda▼J. García
   6. 74'
      BOL
      Substitution
      ▲Limberg Gutiérrez▼Alberto Guitián
   7. 75'
      COL
      Substitution
      ▲J. Rodríguez▼Homer Martinez
   8. 75'
      COL
      Substitution
      ▲L. González▼J. Pajoy
   9. 78'
      BOL
      Yellow card
      L. Ramos
   10. 84'
       BOL
       Substitution
       ▲Armando Sadiku▼L. Ramos
   11. 84'
       COL
       Substitution
       ▲C. Valencia▼Teófilo Gutiérrez