Independiente del Valle beat Gremio 2-1. The winner had to work for it: 2 from 16 shots. Gremio played with ten from minute 59. L. Faravelli scored 2 goals. Best on the pitch was L. Faravelli, rated 8.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   ECU 3-4-3·4-2-3-1 BRA
   Coach: Renato Paiva · Renato GaúchoReferee: N. Pitana📍 Estadio Defensores del Chaco
2. 1. First half
   2. 9'
      BRA
      GOOOAL!Diego SouzaAssist: Alisson
   3. 10'
      ECU
      Yellow card
      P. Vite
   4. 17'
      BRA
      Yellow card
      Tonhão Rodrigues
   5. 26'
      BRA
      Yellow card
      Brenno
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Darlan▼C. Pinares
   3. 47'
      BRA
      Yellow card
      Ruan
   4. 53'
      ECU
      GOOOAL!L. FaravelliAssist: B. Montenegro
   5. 59'
      BRA
      Yellow card
      Ruan
   6. 59'
      BRA
      Red card
      Ruan
   7. 61'
      ECU
      GOOOAL!L. FaravelliPenalty
   8. 62'
      ECU
      Substitution
      ▲B. García▼C. Pellerano
   9. 62'
      BRA
      Substitution
      ▲David Braz▼Diego Souza
   10. 63'
       BRA
       Substitution
       ▲Fernando Henrique▼Lucas Silva
   11. 69'
       ECU
       Substitution
       ▲Jacob Murillo▼C. Ortiz
   12. 69'
       ECU
       Substitution
       ▲J. Sánchez▼A. Hurtado
   13. 71'
       BRA
       Substitution
       ▲Leonardo Chú▼Alisson
   14. 76'
       ECU
       Substitution
       ▲E. Mera▼P. Vite
   15. 76'
       ECU
       Substitution
       ▲J. Escobar▼B. Montenegro
   16. 76'
       BRA
       Substitution
       ▲Bruno Cortêz▼Felipe
   17. 85'
       ECU
       Yellow card
       W. Pacho
   18. 85'
       ECU
       Yellow card
       E. Mera