Independiente del Valle beat Gremio 1-2. The winner had to work for it: 2 from 18 shots. Gremio played with ten from minute 63. C. Ortiz scored 2 goals. Best on the pitch was C. Ortiz, rated 8.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   BRA 4-2-3-1·4-1-4-1 ECU
   Coach: Renato Gaúcho · Renato PaivaReferee: P. Loustau📍 Arena do Grêmio
2. 1. First half
   2. 9'
      BRA
      Yellow card
      Alisson
   3. 18'
      BRA
      Yellow card
      Maicon
   4. 22'
      BRA
      GOOOAL!Jean Pyerre
   5. 45+1'
      ECU
      Yellow card
      W. Pacho
   6. 45+3'
      ECU
      GOOOAL!C. Ortiz
3. 1. Second half
   2. 46'
      ECU
      Substitution
      ▲Jhoanner Chavez▼B. Caicedo
   3. 55'
      BRA
      Substitution
      ▲Pepê▼Alisson
   4. 61'
      BRA
      Yellow card
      Bruno Cortêz
   5. 63'
      BRA
      Yellow card
      Maicon
   6. 63'
      BRA
      Red card
      Maicon
   7. 66'
      ECU
      GOOOAL!C. OrtizAssist: L. Faravelli
   8. 71'
      BRA
      Substitution
      ▲Darlan▼Jean Pyerre
   9. 71'
      BRA
      Substitution
      ▲Luiz Fernando▼Ferreira
   10. 75'
       ECU
       Substitution
       ▲Jacob Murillo▼B. Montenegro
   11. 76'
       ECU
       Yellow card
       A. Hurtado
   12. 76'
       ECU
       Substitution
       ▲B. García▼P. Vite
   13. 80'
       BRA
       Yellow card
       Diego Souza
   14. 80'
       ECU
       Substitution
       ▲A. Landázuri▼A. Hurtado
   15. 82'
       BRA
       Yellow card
       W. Kannemann
   16. 82'
       BRA
       Substitution
       ▲Ricardinho▼Diego Souza
   17. 82'
       BRA
       Substitution
       ▲Lucas Silva▼Matheuzinho
   18. 84'
       ECU
       Substitution
       ▲J. Escobar▼C. Ortiz