Argentinos Juniors beat Club Nacional 2-0. Argentinos Juniors played with ten from minute 81. Best on the pitch was Gabriel Ávalos, rated 7.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   ARG 3-4-1-2·4-2-3-1 URU
   Coach: G. Milito · A. CapuccioReferee: V. Carrillo📍 Estadio Diego Armando Maradona
2. 1. First half
   2. 15'
      ARG
      Yellow card
      J. Gomez
   3. 17'
      URU
      Yellow card
      C. Cándido
   4. 25'
      ARG
      GOOOAL!Gabriel ÁvalosAssist: C. Quintana
   5. 35'
      URU
      Yellow card
      A. D'Alessandro
   6. 36'
      ARG
      Yellow card
      F. Moyano
   7. 41'
      ARG
      Yellow card
      C. Quintana
   8. 45+3'
      URU
      Yellow card
      G. Corujo
3. 1. Second half
   2. 47'
      URU
      Yellow card
      Gonzalo Bergessio
   3. 61'
      ARG
      Substitution
      ▲G. Florentin▼G. Carabajal
   4. 72'
      ARG
      Substitution
      ▲M. Romero▼J. Gomez
   5. 72'
      ARG
      Substitution
      ▲E. Herrera▼Gabriel Ávalos
   6. 75'
      URU
      Yellow card
      Leandro Fernandez
   7. 79'
      URU
      Substitution
      ▲G. Vega▼B. Ocampo
   8. 80'
      URU
      Substitution
      ▲N. Marichal▼G. Corujo
   9. 80'
      URU
      Substitution
      ▲C. Almeida▼C. Cándido
   10. 80'
       URU
       Substitution
       ▲E. Martinez▼J. Trasante
   11. 81'
       ARG
       Yellow card
       C. Quintana
   12. 81'
       ARG
       Red card
       C. Quintana
   13. 83'
       ARG
       Substitution
       ▲J. Cabrera▼Gabriel Hauche
   14. 88'
       ARG
       GOOOAL!E. HerreraAssist: C. Florentín