Junior and Santa Fe drew 1-1. Junior controlled the ball — 58% possession — but had nothing to show for it. Santa Fe played with ten from minute 71. Best on the pitch was F. Hinestroza, rated 7.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   COL 4-2-3-1·4-2-3-1 COL
   Coach: L. Perea · H. RiveraReferee: J. Valenzuela📍 Estadio Metropolitano Roberto Meléndez
2. 1. First half
   2. 6'
      COL
      Yellow card
      F. Ángel
   3. 17'
      COL
      Yellow card
      Jhon Arias
   4. 24'
      COL
      Yellow card
      Carlos Arboleda
   5. 29'
      COL
      Yellow card
      F. Torijano
   6. 31'
      COL
      GOOOAL!F. Hinestroza
   7. 35'
      COL
      GOOOAL!K. OsorioPenalty
3. 1. Second half
   2. 46'
      COL
      Substitution
      ▲Larry Vásquez▼F. Ángel
   3. 46'
      COL
      Substitution
      ▲G. Fuentes▼E. Velasco
   4. 54'
      COL
      Substitution
      ▲J. Velásquez▼J. Caballero
   5. 62'
      COL
      Substitution
      ▲D. Rosero Valencia▼G. Mera
   6. 68'
      COL
      Substitution
      ▲A. Rentería▼Jorge Ramos
   7. 70'
      COL
      Substitution
      ▲L. González▼J. Pajoy
   8. 71'
      COL
      Yellow card
      Carlos Arboleda
   9. 71'
      COL
      Red card
      Carlos Arboleda
   10. 74'
       COL
       Substitution
       ▲C. Porras▼K. Osorio
   11. 86'
       COL
       Substitution
       ▲C. Valencia▼Homer Martinez