Santos beat The Strongest 5-0. Best on the pitch was Felipe Jonatan, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   BRA —·4-2-3-1 BOL
   Coach: — · L. OrozcoReferee: C. Garay📍 Estádio Urbano Caldeira
2. 1. First half
   2. 1'
      BRA
      GOOOAL!MarinhoAssist: Gabriel Pirani
   3. 13'
      BOL
      Yellow card
      Jaime Arrascaita
   4. 26'
      BRA
      GOOOAL!Gabriel PiraniAssist: Felipe Jonatan
   5. 43'
      BRA
      GOOOAL!ViniciusAssist: Felipe Jonatan
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Kaio Jorge▼Marcos Leonardo
   3. 46'
      BRA
      Substitution
      ▲Madson▼Pará
   4. 51'
      BRA
      Yellow card
      Kaiky
   5. 58'
      BOL
      Substitution
      ▲Fran Pastor▼Rudy Cardozo
   6. 59'
      BRA
      GOOOAL!Lucas BragaAssist: Marinho
   7. 61'
      BRA
      Substitution
      ▲Ângelo▼Lucas Braga
   8. 75'
      BRA
      Substitution
      ▲Kevin Malthus▼Vinicius
   9. 75'
      BOL
      Substitution
      ▲Rolando Blackburn▼J. Reinoso
   10. 75'
       BOL
       Substitution
       ▲J. Chura▼Jaime Arrascaita
   11. 82'
       BOL
       Yellow card
       D. Wayar
   12. 83'
       BRA
       GOOOAL!Kevin Malthus
   13. 85'
       BRA
       Substitution
       ▲Jonathan Copete▼Felipe Jonatan
   14. 90+1'
       BOL
       Substitution
       ▲David Mateos▼J. Sagredo