Independiente del Valle beat Universitario 4-0. J. Sánchez scored 2 goals. Best on the pitch was J. Sánchez, rated 8.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   ECU 3-5-2·4-3-3 PER
   Coach: Renato Paiva · Á. ComizzoReferee: A. Cunha📍 Estadio Rodrigo Paz Delgado
2. 1. First half
   2. 10'
      PER
      Yellow card
      J. Murrugarra
   3. 23'
      PER
      Yellow card
      G. Barreto
   4. 33'
      ECU
      Yellow card
      B. Caicedo
   5. 38'
      ECU
      Yellow card
      A. Landázuri
   6. 38'
      ECU
      Substitution
      ▲J. Sánchez▼B. Caicedo
   7. 45+3'
      ECU
      GOOOAL!J. SánchezAssist: P. Vite
3. 1. Second half
   2. 46'
      PER
      Substitution
      ▲Hernan Novick▼G. Barreto
   3. 61'
      ECU
      GOOOAL!Jacob Murillo
   4. 65'
      ECU
      Substitution
      ▲C. Ortiz▼J. Escobar
   5. 65'
      PER
      Substitution
      ▲G. Larios▼A. Valera
   6. 69'
      PER
      Substitution
      ▲R. Guarderas▼L. Urruti
   7. 73'
      ECU
      GOOOAL!J. SánchezAssist: P. Vite
   8. 77'
      ECU
      Substitution
      ▲E. Mera▼L. Faravelli
   9. 77'
      ECU
      Substitution
      ▲B. Montenegro▼Jacob Murillo
   10. 77'
       ECU
       Substitution
       ▲Jhoanner Chavez▼A. Hurtado
   11. 85'
       ECU
       GOOOAL!C. OrtizAssist: J. Chávez