Argentinos Juniors beat Atletico Nacional 0-2. The winner had to work for it: 2 from 14 shots. Atletico Nacional played with ten from minute 71. Gabriel Ávalos scored 2 goals. Best on the pitch was Gabriel Ávalos, rated 8.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   COL 4-2-3-1·3-4-1-2 ARG
   Coach: A. Guimarães · G. MilitoReferee: J. Valenzuela📍 Estadio Manuel Ferreira
2. 1. First half
   2. 2'
      COL
      Yellow card
      Brayan Rovira
   3. 6'
      ARG
      Yellow card
      K. Mac Allister
   4. 18'
      ARG
      GOOOAL!Gabriel Ávalos
   5. 32'
      ARG
      Yellow card
      Elías Gómez
3. 1. Second half
   2. 49'
      ARG
      Yellow card
      F. Moyano
   3. 63'
      ARG
      Yellow card
      C. Quintana
   4. 64'
      COL
      Yellow card
      E. Olivera
   5. 68'
      COL
      Substitution
      ▲Alex Castro▼Brayan Rovira
   6. 71'
      COL
      Yellow card
      E. Olivera
   7. 71'
      COL
      Red card
      E. Olivera
   8. 78'
      COL
      Substitution
      ▲J. Alvez▼J. Duque
   9. 80'
      ARG
      GOOOAL!Gabriel Ávalos
   10. 81'
       ARG
       Substitution
       ▲M. Romero▼J. Gomez
   11. 81'
       ARG
       Substitution
       ▲M. Coronel▼Gabriel Hauche
   12. 84'
       COL
       Yellow card
   13. 84'
       ARG
       Yellow card
   14. 86'
       ARG
       Yellow card
       Miguel Torren
   15. 87'
       ARG
       Substitution
       ▲E. Herrera▼Gabriel Ávalos
   16. 87'
       ARG
       Substitution
       ▲G. Carabajal▼G. Florentin
   17. 89'
       COL
       Substitution
       ▲Vladimir Hernández▼J. Barrera
   18. 90+3'
       ARG
       Substitution
       ▲Fausto Vera▼F. Moyano