Vélez Sarsfield beat LDU de Quito 3-1. LDU de Quito played with ten from minute 87. Best on the pitch was L. Janson, rated 8.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   ARG 4-2-3-1·4-2-3-1 ECU
   Coach: M. Pellegrino · P. RepettoReferee: A. Matonte📍 Estadio José Amalfitani
2. 1. First half
   2. 24'
      ECU
      Yellow card
      Jhojan Julio
   3. 45'
      ARG
      GOOOAL!Thiago AlmadaAssist: L. Janson
3. 1. Second half
   2. 59'
      ECU
      Substitution
      ▲Matías Zunino▼A. Muñoz
   3. 67'
      ARG
      Substitution
      ▲R. Centurión▼Thiago Almada
   4. 67'
      ARG
      Substitution
      ▲M. Brizuela▼A. Bouzat
   5. 69'
      ARG
      GOOOAL!L. JansonAssist: R. Centurión
   6. 70'
      ARG
      Yellow card
      P. Galdames
   7. 70'
      ECU
      Substitution
      ▲L. Piovi▼L. Villarruel
   8. 72'
      ARG
      Yellow card
      J. Lucero
   9. 74'
      ECU
      Substitution
      ▲Luis Ayala▼C. Cruz
   10. 74'
       ECU
       Substitution
       ▲Cristian Martínez▼Jhojan Julio
   11. 76'
       ECU
       Yellow card
       J. Alcivar
   12. 77'
       ARG
       Substitution
       ▲M. de los Santos▼F. Ortega
   13. 78'
       ECU
       GOOOAL!Matías ZuninoAssist: C. Martínez
   14. 86'
       ARG
       Substitution
       ▲Federico Mancuello▼A. Mulet
   15. 87'
       ECU
       Red card
       L. Piovi
   16. 87'
       ARG
       Substitution
       ▲Cristian Tarragona▼J. Lucero
   17. 90+3'
       ARG
       GOOOAL!Federico Mancuello