Olimpia beat Always Ready 1-2. Always Ready controlled the ball — 68% possession — but had nothing to show for it. The winner had to work for it: 2 from 17 shots. Best on the pitch was Rodrigo Ramallo, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   BOL 4-3-3·4-3-3 PAR
   Coach: S. Núñez · S. OrtemanReferee: D. Herrera📍 Estadio Hernando Siles
2. 1. First half
   2. 23'
      PAR
      GOOOAL!W. GonzálezAssist: I. Torres
   3. 42'
      BOL
      GOOOAL!Rodrigo RamalloAssist: J. Sanguinetti
   4. 43'
      BOL
      Substitution
      ▲Samuel Galindo▼Juan Arce
3. 1. Second half
   2. 46'
      PAR
      Substitution
      ▲A. Silva▼Hugo Quintana
   3. 50'
      BOL
      Yellow card
      Samuel Galindo
   4. 58'
      PAR
      Substitution
      ▲I. Pitta▼W. González
   5. 65'
      PAR
      Substitution
      ▲J. Santacruz▼B. Ojeda
   6. 65'
      PAR
      Substitution
      ▲Nestor Camacho▼J. Recalde
   7. 68'
      PAR
      Yellow card
      Richard Ortiz
   8. 68'
      PAR
      Yellow card
      I. Torres
   9. 71'
      BOL
      Substitution
      ▲J. Mosquera▼Cristian Machado
   10. 71'
       BOL
       Substitution
       ▲Robert Hernandez▼Edemir Rodriguez
   11. 72'
       BOL
       Yellow card
       Nelson Cabrera
   12. 75'
       PAR
       Yellow card
       A. Aguilar
   13. 81'
       BOL
       Substitution
       ▲C. Algaranaz▼Javier Sanguinetti
   14. 81'
       BOL
       Substitution
       ▲Vander Vieira▼M. Ovejero
   15. 86'
       BOL
       Yellow card
       Robert Hernandez
   16. 90+2'
       PAR
       Substitution
       ▲R. Rojas▼I. Torres
   17. 90+3'
       PAR
       GOOOAL!A. SilvaAssist: N. Camacho