Club Nacional beat U. Catolica 1-0. U. Catolica controlled the ball — 65% possession — but had nothing to show for it. Best on the pitch was S. Rochet, rated 7.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   URU 4-1-4-1·4-3-3 CHI
   Coach: A. Capuccio · G. PoyetReferee: Raphael Claus📍 Estadio Gran Parque Central
2. 1. First half
   2. 29'
      URU
      GOOOAL!B. Ocampo
   3. 34'
      CHI
      Yellow card
      M. Nunez
   4. 40'
      URU
      Yellow card
      Á. Gabrielli
3. 1. Second half
   2. 46'
      URU
      Substitution
      ▲A. Trezza▼A. D'Alessandro
   3. 52'
      URU
      Yellow card
      A. Trezza
   4. 52'
      CHI
      Substitution
      ▲Clemente Montes▼G. Lezcano
   5. 62'
      CHI
      Substitution
      ▲Francisco Silva▼I. Saavedra
   6. 62'
      CHI
      Substitution
      ▲A. Parot▼Juan Cornejo
   7. 65'
      CHI
      Yellow card
      Clemente Montes
   8. 73'
      CHI
      Yellow card
      F. Zampedri
   9. 77'
      CHI
      Substitution
      ▲Felipe Gutiérrez▼L. Aued
   10. 77'
       CHI
       Substitution
       ▲J. Leiva▼B. Ampuero
   11. 82'
       URU
       Substitution
       ▲Rafael García▼Leandro Fernandez
   12. 88'
       URU
       Substitution
       ▲Ignacio Lores▼B. Ocampo
   13. 90+4'
       URU
       Yellow card