Universitario beat Independiente del Valle 3-2. Independiente del Valle controlled the ball — 64% possession — but had nothing to show for it. A. Valera scored 2 goals. Best on the pitch was A. Valera, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   PER 5-3-2·3-4-1-2 ECU
   Coach: Á. Comizzo · Renato PaivaReferee: P. Maza📍 Estadio Monumental
2. 1. First half
   2. 8'
      ECU
      GOOOAL!J. SánchezAssist: C. Pellerano
   3. 20'
      PER
      GOOOAL!A. ValeraAssist: A. Corzo
3. 1. Second half
   2. 48'
      PER
      GOOOAL!A. Valera
   3. 59'
      ECU
      GOOOAL!C. OrtizAssist: R. Schunke
   4. 60'
      ECU
      Substitution
      ▲Jacob Murillo▼J. Sánchez
   5. 65'
      PER
      Substitution
      ▲J. Zevallos▼R. Guarderas
   6. 67'
      PER
      Yellow card
      J. Rugel
   7. 70'
      ECU
      Yellow card
      L. Segovia
   8. 71'
      PER
      GOOOAL!N. QuinaAssist: A. Corzo
   9. 72'
      ECU
      Yellow card
      C. Ortiz
   10. 72'
       ECU
       Substitution
       ▲Jhoanner Chavez▼L. Segovia
   11. 72'
       ECU
       Substitution
       ▲B. García▼L. Faravelli
   12. 75'
       ECU
       Yellow card
       C. Pellerano
   13. 78'
       PER
       Yellow card
       A. Corzo
   14. 80'
       ECU
       Substitution
       ▲E. Mera▼P. Vite
   15. 85'
       PER
       Substitution
       ▲Hernan Novick▼Armando Alfageme