Argentinos Juniors beat Atletico Nacional 1-0. The winner had to work for it: 1 from 12 shots. Best on the pitch was B. Perlaza, rated 7.6.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   ARG 3-5-2·3-5-1-1 COL
   Coach: G. Milito · A. GuimarãesReferee: Bruno Arleu de Araujo📍 Estadio Diego Armando Maradona
2. 1. First half
   2. 34'
      ARG
      Yellow card
      Miguel Torren
   3. 43'
      COL
      Yellow card
      A. Andrade
3. 1. Second half
   2. 49'
      COL
      Yellow card
      J. Alvez
   3. 73'
      ARG
      Substitution
      ▲G. Carabajal▼J. Sandoval
   4. 73'
      ARG
      Substitution
      ▲E. Herrera▼Gabriel Ávalos
   5. 80'
      ARG
      Substitution
      ▲Lucas Villalba▼Elías Gómez
   6. 82'
      COL
      Substitution
      ▲Vladimir Hernández▼Alex Castro
   7. 83'
      ARG
      Yellow card
      G. Carabajal
   8. 87'
      ARG
      Substitution
      ▲D. Sosa▼G. Florentin
   9. 88'
      ARG
      Substitution
      ▲M. Romero▼J. Gomez
   10. 88'
       COL
       Substitution
       ▲N. Moreno▼A. Andrade
   11. 90'
       ARG
       GOOOAL!E. HerreraAssist: K. Mac Allister
   12. 90+3'
       ARG
       Yellow card
       D. Sosa
   13. 90+3'
       COL
       Substitution
       ▲Brayan Cordoba▼S. Gomez