U. Catolica beat Atletico Nacional 2-0. Atletico Nacional controlled the ball — 63% possession — but had nothing to show for it. The winner had to work for it: 2 from 14 shots. Best on the pitch was S. Perez, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   CHI 5-3-2·4-2-3-1 COL
   Coach: G. Poyet · A. GuimarãesReferee: Wilton Pereira Sampaio📍 Estadio San Carlos de Apoquindo
2. 1. First half
   2. -5'
      COL
      Yellow card
      Vladimir Hernández
   3. 9'
      CHI
      GOOOAL!L. AuedAssist: M. Nuñez
   4. 22'
      CHI
      Yellow card
      D. Valencia
   5. 36'
      CHI
      Yellow card
      I. Saavedra
   6. 45+2'
      COL
      Yellow card
      Y. Candelo
3. 1. Second half
   2. 52'
      CHI
      Yellow card
      M. Nunez
   3. 62'
      COL
      Substitution
      ▲Alex Castro▼N. Moreno
   4. 67'
      CHI
      Yellow card
      S. Perez
   5. 68'
      COL
      Yellow card
      Brayan Rovira
   6. 74'
      CHI
      Substitution
      ▲Clemente Montes▼Edson Puch
   7. 74'
      COL
      Substitution
      ▲Brayan Cordoba▼E. Olivera
   8. 74'
      COL
      Substitution
      ▲J. Alvez▼Y. Candelo
   9. 78'
      CHI
      Substitution
      ▲Felipe Gutiérrez▼L. Aued
   10. 79'
       CHI
       GOOOAL!D. ValenciaAssist: C. Montes
   11. 90+1'
       CHI
       Yellow card
       T. Asta-Buruaga
   12. 90+2'
       CHI
       Substitution
       ▲Francisco Silva▼J. Leiva
   13. 90+2'
       CHI
       Substitution
       ▲A. Parot▼Juan Cornejo