LDU de Quito beat Union La Calera 5-2. L. Amarilla scored 2 goals. Best on the pitch was Billy Arce, rated 8.9.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   ECU 4-2-3-1·4-1-4-1 CHI
   Coach: P. Repetto · L. MarcogiuseppeReferee: C. Betancur📍 Estadio Rodrigo Paz Delgado
2. 1. First half
   2. 15'
      CHI
      Own goalM. Fernandez
   3. 28'
      ECU
      GOOOAL!L. AmarillaAssist: A. Muñoz
   4. 33'
      ECU
      GOOOAL!L. Amarilla
3. 1. Second half
   2. 46'
      CHI
      Substitution
      ▲Gonzalo Castellani▼B. Liuzzi
   3. 46'
      CHI
      Substitution
      ▲Jeisson Vargas▼E. Valencia
   4. 46'
      CHI
      Substitution
      ▲S. Ramírez▼M. Cavalleri
   5. 54'
      CHI
      GOOOAL!Sebastián SáezAssist: J. Vargas
   6. 58'
      ECU
      GOOOAL!Billy Arce
   7. 60'
      ECU
      GOOOAL!Billy ArceAssist: J. Quinteros
   8. 63'
      ECU
      Substitution
      ▲Joseph Espinoza▼J. Alcivar
   9. 64'
      ECU
      Substitution
      ▲Cristian Martínez▼A. Muñoz
   10. 64'
       CHI
       Substitution
       ▲A. Moreno▼M. Fernandez
   11. 72'
       ECU
       Substitution
       ▲F. Ventura▼José Quintero
   12. 72'
       ECU
       Substitution
       ▲Matías Zunino▼L. Amarilla
   13. 80'
       ECU
       Substitution
       ▲M. Corozo▼Anderson Ordóñez
   14. 90+2'
       CHI
       GOOOAL!Sebastián SáezAssist: N. Orellana