Fluminense beat Cerro Porteno 0-2. Cerro Porteno controlled the ball — 62% possession — but had nothing to show for it. The winner had to work for it: 2 from 15 shots. Best on the pitch was Egídio, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2021
   PAR 4-2-3-1·4-2-3-1 BRA
   Coach: F. Arce · Roger MachadoReferee: F. Tello📍 Estadio General Pablo Rojas
2. 1. First half
   2. 27'
      PAR
      Yellow card
      A. Duarte
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Luiz Henrique▼Gabriel Teixeira
   3. 49'
      BRA
      GOOOAL!NenêAssist: Caio Paulista
   4. 61'
      BRA
      GOOOAL!EgídioAssist: Caio Paulista
   5. 66'
      PAR
      Substitution
      ▲D. Bobadilla▼R. Carrascal
   6. 66'
      PAR
      Substitution
      ▲E. Gimenez▼Mateus Gonçalves
   7. 72'
      BRA
      Substitution
      ▲Lucca▼Abel Hernández
   8. 73'
      BRA
      Substitution
      ▲J. Cazares▼Nenê
   9. 79'
      PAR
      VAR review
      C. Aquino
   10. 82'
       PAR
       Substitution
       ▲F. Romero▼A. Espinola
   11. 82'
       PAR
       Substitution
       ▲Adrián Martínez▼R. Morales
   12. 82'
       BRA
       Substitution
       ▲Kayky▼Caio Paulista
   13. 89'
       PAR
       Substitution
       ▲Luis Fariña▼M. Boselli
   14. 90+1'
       BRA
       Substitution
       ▲Wellington▼Andre