Fluminense beat Millonarios 1-2. The winner had to work for it: 2 from 14 shots. Millonarios played with ten from minute 19. Best on the pitch was Luiz Henrique, rated 8.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   COL 4-2-3-1·4-1-4-1 BRA
   Coach: A. Gamero · Abel BragaReferee: D. Herrera📍 Estadio Nemesio Camacho El Campín
2. 1. First half
   2. 7'
      COL
      GOOOAL!E. SosaAssist: D. Ruiz
   3. 10'
      BRA
      Yellow card
      Felipe Melo
   4. 10'
      COL
      Yellow card
      E. Sosa
   5. 19'
      COL
      Yellow card
      E. Sosa
   6. 19'
      COL
      Red card
      E. Sosa
   7. 23'
      BRA
      Yellow card
      Calegari
   8. 38'
      BRA
      Substitution
      ▲Germán Cano▼Fred
   9. 43'
      BRA
      GOOOAL!David BrazAssist: Luiz Henrique
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Jhon Arias▼Willian
   3. 52'
      COL
      Yellow card
      A. Llinas
   4. 53'
      BRA
      Yellow card
      David Braz
   5. 64'
      COL
      Substitution
      ▲J. Valencia▼D. Herazo
   6. 65'
      BRA
      Substitution
      ▲Ganso▼Felipe Melo
   7. 65'
      BRA
      Substitution
      ▲M. Pineida▼Cris Silva
   8. 76'
      BRA
      Substitution
      ▲Martinelli▼Yago
   9. 77'
      BRA
      GOOOAL!Germán CanoAssist: Luiz Henrique
   10. 83'
       COL
       Substitution
       ▲R. Celis▼Larry Vásquez
   11. 90+2'
       COL
       Substitution
       ▲Elvis Perlaza▼A. Roman
   12. 90+2'
       COL
       Substitution
       ▲E. Guerra▼D. Ruiz
   13. 90+2'
       COL
       Substitution
       ▲J. Pereira▼D. Silva