Universidad Catolica and The Strongest drew 0-0. Universidad Catolica controlled the ball — 71% possession — but had nothing to show for it. The Strongest played with ten from minute 36. Best on the pitch was F. Martinez, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   ECU 4-2-3-1·4-4-2 BOL
   Coach: M. Rondelli · C. DíazReferee: A. Matonte📍 Estadio Olímpico Atahualpa
2. 1. First half
   2. 36'
      BOL
      Red card
      M. Prost
   3. 42'
      ECU
      Substitution
      ▲J. Cárdenas▼D. Cuero
   4. 45+2'
      ECU
      Substitution
      ▲L. Loor▼J. Carabalí
3. 1. Second half
   2. 62'
      BOL
      Substitution
      ▲Jaime Arrascaita▼R. Amaral
   3. 68'
      BOL
      Substitution
      ▲J. Reinoso▼E. Triverio
   4. 69'
      BOL
      Yellow card
      J. Reinoso
   5. 74'
      ECU
      Substitution
      ▲R. Rivas▼Cristian Martínez
   6. 74'
      ECU
      Substitution
      ▲W. Cevallos▼S. Zamora
   7. 76'
      ECU
      Yellow card
      R. Rivas
   8. 86'
      BOL
      Yellow card
      G. Viscarra
   9. 90+1'
      BOL
      Substitution
      ▲J. Villamíl▼L. Ursino
   10. 90+6'
       ECU
       Yellow card
       Kevin Minda