Club Nacional beat Vélez Sarsfield 1-2. The winner had to work for it: 2 from 21 shots. Vélez Sarsfield played with ten from minute 18. Emmanuel Gigliotti scored 2 goals. Best on the pitch was Emmanuel Gigliotti, rated 8.3.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   ARG 4-1-4-1·4-2-3-1 URU
   Coach: J. Vaccari · P. RepettoReferee: E. Aquino📍 Estadio José Amalfitani
2. 1. First half
   2. -5'
      ARG
      Yellow card
      E. Insúa
   3. 15'
      ARG
      GOOOAL!J. Soñora
   4. 18'
      ARG
      Red card
      J. Florentín
   5. 24'
      URU
      Yellow card
      S. Rochet
   6. 30'
      URU
      Substitution
      ▲A. Trezza▼Alex Castro
   7. 31'
      URU
      GOOOAL!Emmanuel GigliottiAssist: F. Carballo
   8. 43'
      URU
      Yellow card
      Léo Coelho
3. 1. Second half
   2. 46'
      URU
      Substitution
      ▲Mathías Laborda▼Léo Coelho
   3. 56'
      ARG
      Substitution
      ▲S. Cáseres▼J. Soñora
   4. 59'
      URU
      Yellow card
      J. Rodriguez
   5. 61'
      URU
      Yellow card
      C. Cándido
   6. 63'
      URU
      Substitution
      ▲L. Lozano▼C. Cándido
   7. 63'
      URU
      Substitution
      ▲D. Zabala▼M. Monzeglio
   8. 73'
      ARG
      Substitution
      ▲S. Sosa▼Lucas Pratto
   9. 73'
      ARG
      Substitution
      ▲A. Osorio▼L. Janson
   10. 75'
       URU
       GOOOAL!Emmanuel GigliottiAssist: D. Zabala
   11. 86'
       URU
       Yellow card
       N. Marichal
   12. 86'
       ARG
       Substitution
       ▲F. Diaz▼M. Perrone
   13. 87'
       URU
       Substitution
       ▲Diego Manuel Rodríguez▼Y. Rodríguez
   14. 90+1'
       ARG
       Yellow card
       V. Gomez
   15. 90+6'
       URU
       Yellow card
       B. Ocampo