River Plate beat Colo Colo 1-2. The winner had to work for it: 2 from 16 shots. Best on the pitch was Marco Perez, rated 8.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   CHI 4-2-3-1·4-1-4-1 ARG
   Coach: G. Quinteros · M. GallardoReferee: A. Herrera📍 Estadio Monumental David Arellano
2. 1. First half
   2. 19'
      ARG
      Yellow card
      Milton Casco
   3. 34'
      CHI
      Substitution
      ▲O. Carabalí▼Brayan Cortés
3. 1. Second half
   2. 55'
      ARG
      Substitution
      ▲M. Suárez▼S. Simon
   3. 57'
      ARG
      Yellow card
      Enzo Pérez
   4. 62'
      CHI
      Yellow card
      C. Fuentes
   5. 79'
      CHI
      Substitution
      ▲A. Oroz▼L. Gil
   6. 80'
      ARG
      Yellow card
      Marco Perez
   7. 82'
      CHI
      Yellow card
      G. Costa
   8. 82'
      ARG
      GOOOAL!M. Suárez
   9. 89'
      ARG
      GOOOAL!Marco PerezAssist: J. Álvarez
   10. 90'
       CHI
       Substitution
       ▲C. Villanueva▼C. Fuentes
   11. 90'
       ARG
       Substitution
       ▲Bruno Zuculini▼Enzo Pérez
   12. 90+2'
       CHI
       GOOOAL!J. LuceroAssist: P. Solari