Caracas FC beat Libertad Asuncion 1-0. The winner had to work for it: 1 from 12 shots. Best on the pitch was R. Bogarin, rated 8.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   VEN 4-2-3-1·4-3-3 PAR
   Coach: F. Stifano · D. GarneroReferee: A. Matonte📍 Estadio Olímpico de la UCV
2. 1. First half
   2. 14'
      PAR
      Substitution
      ▲J. Canale Dominguez▼Camilo Mayada
   3. 38'
      VEN
      Substitution
      ▲D. Osio▼Rubert Quijada
3. 1. Second half
   2. 50'
      PAR
      Yellow card
      H. Caballero
   3. 51'
      VEN
      GOOOAL!Samson Olanrewaju AkinyoolaAssist: S. Guarirapa
   4. 54'
      PAR
      Yellow card
      Miguel Samudio
   5. 61'
      VEN
      Yellow card
      S. Guarirapa
   6. 64'
      PAR
      Substitution
      ▲Ivan Franco▼H. Caballero
   7. 65'
      PAR
      Substitution
      ▲Diego Gómez▼A. Bareiro
   8. 66'
      VEN
      Yellow card
      B. Ortega
   9. 66'
      PAR
      Yellow card
      Julio César Enciso
   10. 69'
       VEN
       Yellow card
       C. Suárez
   11. 74'
       VEN
       Substitution
       ▲V. Rodríguez▼B. Ortega
   12. 74'
       VEN
       Substitution
       ▲A. Zambrano▼K. Osei
   13. 85'
       PAR
       Substitution
       ▲G. Aguilar▼Marcelo Díaz
   14. 85'
       PAR
       Substitution
       ▲M. Espinoza▼Miguel Samudio
   15. 89'
       VEN
       Substitution
       ▲M. Rivas▼S. Guarirapa
   16. 90+3'
       VEN
       Yellow card
       V. Rodríguez