Vélez Sarsfield beat Club Nacional 2-3. Best on the pitch was J. Soñora, rated 8.5.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   URU 4-2-3-1·4-2-3-1 ARG
   Coach: P. Repetto · J. VaccariReferee: P. Maza📍 Estadio Gran Parque Central
2. 1. First half
   2. -5'
      URU
      Yellow card
      M. Risso
   3. 15'
      URU
      Yellow card
      Y. Rodríguez
   4. 21'
      URU
      GOOOAL!D. ZabalaAssist: C. Cándido
   5. 33'
      ARG
      Yellow card
      Nicolás Garayalde
   6. 45'
      ARG
      GOOOAL!L. JansonAssist: L. Orellano
3. 1. Second half
   2. 51'
      ARG
      Yellow card
      M. de los Santos
   3. 58'
      URU
      Substitution
      ▲Diego Manuel Rodríguez▼Y. Rodríguez
   4. 60'
      ARG
      GOOOAL!M. de los SantosAssist: J. Soñora
   5. 64'
      ARG
      Substitution
      ▲J. Florentín▼Nicolás Garayalde
   6. 66'
      URU
      Substitution
      ▲L. Otormín▼Alex Castro
   7. 74'
      URU
      Substitution
      ▲L. Lozano▼J. Rodriguez
   8. 74'
      URU
      Substitution
      ▲F. Fagúndez▼A. Trezza
   9. 78'
      ARG
      Substitution
      ▲A. Bouzat▼L. Orellano
   10. 79'
       ARG
       Substitution
       ▲A. Osorio▼Lucas Pratto
   11. 80'
       URU
       Yellow card
       Mathías Laborda
   12. 81'
       ARG
       Yellow card
       J. Soñora
   13. 82'
       ARG
       Yellow card
       A. Bouzat
   14. 83'
       ARG
       Yellow card
       M. Perrone
   15. 87'
       ARG
       Substitution
       ▲M. Pellegrino▼J. Soñora
   16. 89'
       URU
       GOOOAL!Emmanuel GigliottiPenalty
   17. 90+4'
       ARG
       GOOOAL!M. PerroneAssist: A. Osorio