Atletico Paranaense beat Libertad Asuncion 2-1. Libertad Asuncion controlled the ball — 59% possession — but had nothing to show for it. The winner had to work for it: 2 from 12 shots. Best on the pitch was D. Terans, rated 7.7.

1. 0'
   ⚽Kick-off
   CONMEBOL Libertadores 2022
   BRA 4-2-3-1·4-3-3 PAR
   Coach: Luiz Felipe Scolari · D. GarneroReferee: A. Herrera📍 Arena da Baixada
2. 1. First half
   2. 6'
      BRA
      GOOOAL!Vitor RoqueAssist: D. Terans
   3. 20'
      PAR
      GOOOAL!Héctor VillalbaAssist: M. Samudio
   4. 26'
      BRA
      Yellow card
      Christian
   5. 32'
      BRA
      GOOOAL!N. HernándezAssist: T. Cuello
3. 1. Second half
   2. 46'
      BRA
      Substitution
      ▲Erick▼Christian
   3. 55'
      PAR
      Substitution
      ▲William Mendieta▼R. Martínez
   4. 55'
      PAR
      Substitution
      ▲Ivan Franco▼Héctor Villalba
   5. 72'
      PAR
      Yellow card
      Alex Terra
   6. 74'
      BRA
      Substitution
      ▲A. Canobbio▼Pedro Rocha
   7. 77'
      PAR
      Yellow card
      A. Campuzano
   8. 81'
      PAR
      Substitution
      ▲Óscar Cardozo▼Roque Santa Cruz
   9. 81'
      PAR
      Substitution
      ▲B. Merlini▼Diego Gómez
   10. 82'
       BRA
       Substitution
       ▲Vitor Bueno▼D. Terans
   11. 82'
       BRA
       Substitution
       ▲Rômulo▼Vitor Roque
   12. 88'
       PAR
       Substitution
       ▲I. Piris▼Camilo Mayada
   13. 89'
       BRA
       Substitution
       ▲Matheus Babi▼T. Cuello