Huachipato beat Antofagasta 3-0. Antofagasta played with ten from minute 39. Best on the pitch was M. Parra, rated 9.0.

1. 0'
   ⚽Kick-off
   CONMEBOL Sudamericana 2021
   CHI 4-3-3·4-4-1-1 CHI
   Coach: J. Luvera · J. RiberaReferee: P. Maza📍 Estadio CAP
2. 1. First half
   2. 9'
      CHI
      GOOOAL!C. Martínez
   3. 39'
      CHI
      Red card
      L. Soza
   4. 42'
      CHI
      Yellow card
      Andres Robles
   5. 45'
      CHI
      Yellow card
      A. Cuadra
   6. 45'
      CHI
      Yellow card
      D. Orellana
3. 1. Second half
   2. 46'
      CHI
      Substitution
      ▲P. Magalhaes▼A. Cuadra
   3. 61'
      CHI
      Substitution
      ▲N. Baeza▼M. Rodriguez
   4. 64'
      CHI
      Yellow card
      C. Martínez
   5. 66'
      CHI
      Substitution
      ▲Byron Nieto▼J. Flores
   6. 66'
      CHI
      Substitution
      ▲I. Ledezma▼D. Orellana
   7. 67'
      CHI
      GOOOAL!W. MazzanttiAssist: I. Poblete
   8. 76'
      CHI
      Yellow card
      S. Cordero
   9. 79'
      CHI
      Substitution
      ▲A. Uribe▼Eduard Bello
   10. 83'
       CHI
       Substitution
       ▲N. Silva▼W. Mazzantti
   11. 83'
       CHI
       Substitution
       ▲C. Huanca▼J. Altamirano
   12. 86'
       CHI
       GOOOAL!N. SilvaAssist: M. Parra
   13. 87'
       CHI
       Substitution
       ▲J. Córdova▼C. Martínez